White Sox vs. Rays odds, line, prediction: 2022 MLB picks, April 16 best bets from proven computer model - CBSSports.com

The second game of the three-game series between the Tampa Bay Rays (5-2) and the Chicago White Sox (4-4) will get underway on Saturday afternoon. The Rays won the first contest 3-2 on Friday evening. The White Sox will look to bounce back to end their three-game losing streak. Corey Kluber (0-0, 0.00 ERA) gets the start for Tampa Bay, while Michael Kopech (0-0, 2.25 ERA) is on the other side for Chicago. 

First pitch is set for 2:10 p.m. ET. The latest Rays vs. White Sox odds from Caesars Sportsbook lists Chicago as the -130 money-line favorite (risk $130 to win $100), while Tampa Bay is a +110 underdog. The over-under for total runs scored is 8.5. Before making any White Sox vs. Rays picks, you need to check out the latest MLB predictions and betting advice from the SportsLine Projection Model.

This model, which simulates every game 10,000 times, enters Week 2 of the 2022 season on a 216-181 roll on top-rated MLB money-line picks that dates back to last season, returning over $900 for $100 players. Anyone following it has seen huge returns.

Now, the model has locked in on White Sox vs. Rays, and just locked in its picks and MLB predictions. You can visit SportsLine now to see the model's picks. Here are the MLB odds and trends for Rays vs. White Sox:

  • White Sox vs. Rays money line: Chicago -130, Tampa Bay +110
  • White Sox vs. Rays run-line: Chicago -1.5 (+150)
  • White Sox vs. Rays over-under: 8.5 runs
  • TB: Rays are 7-1 in their last eight after scoring two runs or fewer in their previous game
  • CHW: White Sox are 5-1 in their last six overall
Featured Game | Chicago White Sox vs. Tampa Bay Rays

Why you should back the Rays

Second baseman Brandon Lowe is a patient hitter who stays disciplined. Lowe knows how to draw walks but can also hit the long ball. The 2019 All-Star has a batting average of .267 with a team-high three homers and six RBIs. He's finished with two-plus hits in three of his last six games. On April 14, Lowe went 2-for-4 with a two-run home run.

First baseman Ji-Man Choi has solid power and can hit the baseball to all gaps on the field. Choi also runs the bases well and can snag a few steals. He currently leads Tampa Bay in batting average (.526) with two homers, six RBIs and an on-base percentage (.640). On April 12, he logged three hits, including a three-run bomb. 

Why you should back the White Sox

Designated hitter Andrew Vaughn is a hard-hitting slugger who brings power, patience and precision to the batters' box. Vaughn has a compact swing that allows him to drive the baseball to parts of the field and find gaps. He currently has a batting average of .350 with two home runs and six RBIs. On April 10, Vaughn went 2-for-4 with a homer and four RBIs.

First baseman Jose Abreu has struggled to start the season but has an explosive bat. Abreu is a complete hitter with great power and bat control. The three-time All-Star has the ability to consistently produce runs. On April 10, Abreu had two hits, two RBIs and scored three runs. 

How to make White Sox vs. Rays picks

SportsLine's model is leaning over on the run total, as the simulation suggests the teams will combine for 8.7 runs. It also says one side of the money line has all the value. You can only get the model's pick at SportsLine

So who wins Rays vs. White Sox? And which side of the money line has all the value? Visit SportsLine now to see which side to jump on, all from the advanced model that has crushed its top-rated MLB picks, and find out.

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